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Introduction
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The MR Modality and Perfusion/Diffusion Imaging
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Outline/Study Content
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Current Applications of Perfusion and Diffusion Imaging:
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MRI and Cerebral Ischemia
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Definitions of Neurological Conditions:
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The Physiological Process of Perfusion and Diffusion:
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The Capillaries' Function
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The Perfusion Process
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The Perfusion Process (con't.)
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Cellular Diffusion Process
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Review of Cellular Physiology
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Cellular Pathophysiology of Acute Ischemia
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Effects of Reduced Blood Flow
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Breakdown of Blood Brain Barrier
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Difference between Infracted Area and Penumbra
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Acute Intervention Goals
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Review of Pathophysiology of Acute Ischemia
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Perfusion Imaging
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Mechanisms of Perfusion Scan Techniques
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Mechanisms of Perfusion Scan Techniques (con't.)
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Analysis of Perfusion Scans: rCBV Calculation
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TTP and TO Maps
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Examples of Perfusion Maps
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Additional Applications of Perfusion Imaging: Overview
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Myocardial Perfusion
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Carotid Artery Stenosis
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The Diffusion Process: Overview
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Diffusion Coefficients
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Apparent Diffusion Coefficient
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Physical Principles of Diffusion Imaging: Overview
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Principles
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Examples of Diffusion Pulse Sequence
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Beginning of the Diffusion Pulse Sequence
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Dephasing of Protons
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Dephasing Protons (example #2)
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Rephasing of Protons
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b Values
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Diffusion-weighted Images and ADC Maps: Overview
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Anisotropy
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Acute Stroke Examination
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Apparent Diffusion Coefficient
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Diffusion Imaging Methods: Overview
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Motion Sensitivity
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Motion Compensation Techniques
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Future Applications of Diffusion imaging: Overview
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Spine Applications
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Whole Body Imaging
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Diffusion Tensor Applications
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Conclusion
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Conclusion
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Acknowledgments
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Contributors
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Bibliography
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